My first pack was a 2nd generation osprey aether 85, went over 400 miles of backpacking with that.
When I wanted to go lighter I first tried a ula catalyst, just that for another several hundred but I never found it comfortable and got rid of it.
Then I got an aether 70 in the xl size which fit very well but still so heavy. Then I got a granite gear crown. Did a couple hundred miles in both.
The crown was comfortable but it had a floppy framesheet which required careful pack and when not reasonably full could be a pain. I also tried a elemental horizon aquilo which was about the same weight as the crown but had a rigid frame.
Finally I got a unaweep backpack from seekoutside. Only a little over 3 pounds and the most comfortable out of all of them. I got rid of all my other packs and bought a second.