I have a homemade Jardine style synthetic quilt, a couple of GoLites, and the Nunatak Arc Alpinist. They have all served me well. I originally made the synthetic quilt for fear of getting down wet, but have honed my skills enough to trust myself with down. GoLite quilts are cheaper than Nunatak, but that's because they are made in China. I like to vote with my dollars and support North American companies as much as possible, so I'm sticking with Nunatak from now on. Their quilts are amazing. The only thing I don't like about them is the straps that hold it in place. I cut those off and now have strips of nylon (like wings!) sewn along the sides. This way I can tuck the wings under my body and hold it in place, and getting up to pee is much easier.
The only time I use a traditional sleeping bag is in severe cold. The San Juan range in Colorado along the CDT comes to mind here. This year I might experiment with a bivy sack to boost my quilt's temperature rating.