Re genetics--I know that breeds that have been indiscriminately bred (over-bred) solely for profit have ended up with many more physical problems, e.g. hip dysplasia, retinopathy than much less popular breeds. I have two such dogs. My third dog is from an unsung breed. When locating a pup of this breed I had many fewer concerns about inherited problems. The breed club does not seek to advance its popularity for this reason, among others.
Genetics is not my forte', but a look at the statistics comparing popularity and inherited disorders is enlightening. My thanks to all you experts who compile all this info for us prospective owner/companions.
The Catahoula is also an unheralded breed. I am just enquiring about it from an owner, rather than relying on what others write about it.