Antibiotics often don't help chronic Lyme Disease

[tdoczi]

https://www.lewrockwell.com/2016/02/...ry-zika-virus/

Here is the link.

It explains how lyme avoids antibiotics and that the toxins it produces are what causes the symptoms.

how much do ya know about the guy who that site is named after? if you knew much, you might not be so quick to cite anything on his website. and this is from someone who likes the guy.

read any good 9-11 conspiracy theories while you were looking for that article?

[Don H]

My friend's son got bit by a small deer tick on the back. They believe he picked it up while cutting the grass. They noticed the red ring and the tick embedded. They went to the doctor who started antibiotics. He had the test which showed positive. Within two weeks he was hospitalized and the doctors were telling them he might not live. He still has effects today and this started 6 years ago. Call it what you want but the specialists he goes to calls it Chronic Lyme.

[Brewguy]

how much do ya know about the guy who that site is named after? if you knew much, you might not be so quick to cite anything on his website. and this is from someone who likes the guy.

read any good 9-11 conspiracy theories while you were looking for that article?

I know lots about the web site. There is a lot of good information there. If doctors keep saying they can't fix the problem then why not look for other means?

[tdoczi]

I know lots about the web site. There is a lot of good information there. If doctors keep saying they can't fix the problem then why not look for other means?

from that same website. more good information?

https://www.lewrockwell.com/2015/02/...-than-measles/

its humorous that someone likened (not for the first time on this board either) a "lyme denier" to someone who is anti vaccine. in truth, being anti vaccine and believing in chronic lyme disease seem to walk very much hand in hand.

[Bronk]

After all these years the CDC is still spreading misinformation.

[CamelMan]

The biofilm / resistance thing is real: https://www.nlm.nih.gov/medlineplus/...ry_157467.html

I remember a movie or documentary about this where an independent researcher / doctor discovered this is how it hides, but at the time it was considered a fringe theory.

[tdoczi]

The biofilm / resistance thing is real: https://www.nlm.nih.gov/medlineplus/...ry_157467.html

I remember a movie or documentary about this where an independent researcher / doctor discovered this is how it hides, but at the time it was considered a fringe theory.

"university of new haven researchers" reported in the "european journal of microbiology and immunology."

youll forgive me if i dont stop the presses?

i mean really, can you find 6 things dubious about that article? i bet you can.

beware claims of magical bacteria that behaves in a way no other bacteria ever seen does.

[Traveler]

"university of new haven researchers" reported in the "european journal of microbiology and immunology."

youll forgive me if i dont stop the presses?

i mean really, can you find 6 things dubious about that article? i bet you can.

beware claims of magical bacteria that behaves in a way no other bacteria ever seen does.

I do not argue the issue of sources having low credibility and the need to have both higher credibility and more empirical data in this and other scientific information discussions. However, the last sentence above suggests bacteria is staid and unchanging. There was, at one point not long ago, the concept of a "super bacteria" developing, which was at the time comical to many. The research was correct however, and there are now super bacteria as evidenced by the emergence of Staph infections immune to common antibiotics and terribly aggressive.

Its not magic that causes bacteria to behave in a manner no other bacteria has, its evolutionary. That said, an article about this in an online magazine with UFO discussions and the latest conspiracy angles does not lend a high level of trust in the information.

[Starchild]

Not that I necessarily agree with all swjohnsey says (seldom do)...but...what did happen to chronic fatigue syndrome?...

CFS is a group of symptoms, not a cause. Some of the cause I believe it was found to be a symptom the Epstein Barr virus (or something like that), a very common one that most have usually under control of the immune system, but in some the virus gets a upper hand.

[squeezebox]

Yet another psychosomatic illness.

This guy is a serious idiot and needs to troll somewhere else.
But in a 180 degree way there's a good point about the longer you have Lyme the most serious it becomes, and can lead to permanent damage. Cognative damage happens it's not psycosomatic.
4 eyed's comments are best. Prevention, early detection, early treatment. Also keep in mind some people do not present with a bullseye.

[rafe]

I'm not a doctor and I don't play one on TV. I believe "Lyme" covers many specific illnesses, what's common is that they're spread by ticks.

Found & removed a tick on my shoulder blade last Saturday. It had probably arrived two days earlier on a walk through local woods while it was relatively warm. Doctor is advising "wait and see." As he has done on at least one other similar occasion. He doesn't seem overly alarmed. He didn't send me in for blood samples. I wonder sometimes if he's as proactive about this stuff as he could or should be. Partly my fault too, I didn't bother to tell him about it 'till Monday or Tuesday (four or five days after the bite.)

I think sometimes about that childrens' song, "There ain't no bugs on me."

[CamelMan]

Biofilms are real. I don't see what's wrong with the European Journal of Anything. It's cited by the NIH, which is also a pretty credible source.

[Pedaling Fool]

Biofilms are real. I don't see what's wrong with the European Journal of Anything. It's cited by the NIH, which is also a pretty credible source.

It's true, they are real. I don't see why that's such a hard pill to swallow (pardon the pun). There are far more incredible things in nature.

[tdoczi]

Biofilms are real. I don't see what's wrong with the European Journal of Anything. It's cited by the NIH, which is also a pretty credible source.

do ten seconds of research on that journal, and more so, on the university of new haven. then compare it to other medical news, what sorts of institutes typically perform that sort of research and where that is usually reported and ask yourself why there is no similar study done and published by those institutes. or for that matter why no more respectful journal published this study.

NIH repeated it probably in some sort of catch all manner i would guess.

[X-Pat]

do ten seconds of research on that journal, and more so, on the university of new haven. then compare it to other medical news, what sorts of institutes typically perform that sort of research and where that is usually reported and ask yourself why there is no similar study done and published by those institutes. or for that matter why no more respectful journal published this study.

NIH repeated it probably in some sort of catch all manner i would guess.

I did a little over 10 seconds of research and at first glance couldn't find anything wrong with either the University of New Haven (except that a Raiders coach is an alumn) or the "European Journal of Microbiology and Immunology", unless of course you doubt anything European on instinct.

Care to elaborate?

[Pedaling Fool]

do ten seconds of research on that journal, and more so, on the university of new haven. then compare it to other medical news, what sorts of institutes typically perform that sort of research and where that is usually reported and ask yourself why there is no similar study done and published by those institutes. or for that matter why no more respectful journal published this study.

NIH repeated it probably in some sort of catch all manner i would guess.

I agree with X-Pat, above^^.

Furthermore, I'm not really sure what you're saying other than you think those institutions and the researcher (Eva Sapi http://www.newhaven.edu/faculty-spotlights/eva-sapi/ ) is crap.

It also seems like you're denying biofilms as a real phenomenon as evidenced by your above post (post #27), attributing them to 'magical bacteria'

I'm not sure if Lyme disease bacteria does have this ability to form biofilm, but regardless that doesn't prove that the research is bunk.

Look at how misunderstood Lyme disease is, so if you want to call Dr. Sapi's research bunk, than you might as well call it all bunk, since it's such a hugely misunderstood disease, just see here: http://www.cdc.gov/lyme/postLDS/


Notice in the last paragraph that they say what most medical experts believe...No one has a good grip on this disease, still a lot of research needed.



Excerpt:

It is not uncommon for patients treated for Lyme disease with a recommended 2 to 4 week course of antibiotics to have lingering symptoms of fatigue, pain, or joint and muscle aches at the time they finish treatment. In a small percentage of cases, these symptoms can last for more than 6 months. Although sometimes called "chronic Lyme disease," this condition is properly known as "Post-treatment Lyme Disease Syndrome" (PTLDS).

The exact cause of PTLDS is not yet known. Most medical experts believe that the lingering symptoms are the result of residual damage to tissues and the immune system that occurred during the infection.

[Pedaling Fool]

NIH repeated it probably in some sort of catch all manner i would guess.

That wasn't the first time they repeated it


http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108755/

Biofilms

Another mechanism of chronic infection involves the formation of biofilms.92–98 These adherent polysaccharide-based matrices protect bacteria from the hostile host environment and facilitate persistent infection. Biofilms are responsible for a number of chronic infections, including periodontitis, chronic otitis media, endocarditis, gastrointestinal infection, and chronic lung infection.92–98 Sapi and MacDonald raised the possibility of biofilm formation by B. burgdorferi, and subsequent work has demonstrated these spirochetal formations in culture and in the tick gut.99,100 Combinations of borrelial cysts and putative biofilms have also been noted in patient skin biopsies using focus floating microscopy.101 Biofilm formation is dependent on cyclic di-GMP expression,102,103 and recent studies have shown that B. burgdorferiexpresses this regulatory molecule.104,105 Coordinated steps in the elaboration of biofilms have been demonstrated in other bacteria, and it remains to be seen whether similar molecular processes occur in borrelial strains and whether these processes play a role in persistent infection.106,107

To date no antibiotic treatment exists for biofilm formation. However elucidation of the regulatory steps in the biofilm process should allow development of ‘designer’ antibiotics that interfere with this process.106 It has recently been shown that mutations in genes that regulate biofilm development can interfere with the elaboration of new biofilms and also cause collapse of established biofilm colonies.107 These findings indicate the potential effectiveness of newer antibiotics that target the biofilm regulatory process, suggesting a novel approach to treatment of Lyme disease and other chronic infections.108,109

[Uncle Joe]

No one has a good grip on this disease, still a lot of research needed.

Complete BS! Clearly there are experts right here on WB who understand this disease fully and if consulted could explain the nuances of this disease to doctors.

[rafe]

Lyme disease is real. Chronic Lyme is something else. Article couldn't even get the right kind of tick. I got anaplasmosis in 2011, put me in the hospital in Hersey, PA for a few days because it went untreated for about a month. I they can't find the organism in your body, if antibiotics are effective, it is probably your imagination or something else.

It turns out that some of the tests for Lyme don't test for the organism, but for your body's immune response. And the immune response may be triggered by other stuff going on, or by vaccines you've received.

A few years back I had a bout of Bell's palsy, accompanied (preceded) by severe pain in my jaw and temple (so maybe it was Ramsey-Hunt, whatever.) Come to find out that's one of many symptoms of Lyme. The palsy symptoms cleared up quickly, but there was neurological damage that messed up my balance on that side. I've learned to live with it, but the effect is permanent.

[tdoczi]

I did a little over 10 seconds of research and at first glance couldn't find anything wrong with either the University of New Haven (except that a Raiders coach is an alumn) or the "European Journal of Microbiology and Immunology", unless of course you doubt anything European on instinct.

Care to elaborate?

care to cite one piece of other significant, widely accepted and noteworthy piece of research associated with either institution?

or maybe im just biased because my sister attended UNH and i know it well. theres nothing groundbreaking going on there. they havent scooped the countless numbers of far more reputable and noteworthy bastions of medical research in the country with research that for some reason only a very specific, narrowly focused medical journal in europe would publish.

when you find a study done by something like an ivy league medical school published in JAMA, let me know.