I would suggest either the NPT or the CL-50, ive done both, of course the CL-50 is only a couple or 3 day trip but its a nice trail, also keep in mind that there was a store in wanakena but ive just learned that it is closing its doors for good unless someone else buys it so there is no resupply points along the trail anymore, too bad considering they just opened that trail last yr.
The NPT is better though, but wait till after mid june to go or the black flies will chase you out of the woods or eat you alive. There are 3 towns to pass through on you r way to lake placid for resupply or to pick up mail drops..